"This is a virus that will exploit any opportunity."
According to CP24, Ford will be discussing if a mandatory policy will be put in place for both health care and education workers.
The move comes in response to statements made by the Ontario Medical Association and the Ontario Public School Boards' Association, both of which called on the government to make a change last week.
Ford, who previously rejected the idea of mandatory vaccines, has faced increasing pressure as daily COVID-19 case counts soar above 500.
"This is a virus that will exploit any opportunity, any weakness in the system to mutate and become even more lethal," the premier told reporters at the annual Association of Municipalities of Ontario conference on Monday.
If approved, the province would be following behind the federal government, which has already made vaccines mandatory for federal workers.